Lipoatrophy in a patient on highly purified beef insulin.
نویسندگان
چکیده
منابع مشابه
Lipohypertrophy and lipoatrophy complicating treatment with highly purified bovine and porcine insulins.
Lipoatrophy and lipohypertrophy were the most frequently reported local complications of conventional insulin therapy. Early reports following the introduction of highly purified insulins suggested a reduction in the frequency of lipohypertrophy and lipoatrophy. Since highly purified insulins have been in common usage for 10 years, the present frequency of these complications was assessed in a ...
متن کاملHuman insulin analog--induced lipoatrophy.
OBJECTIVE To characterize the pathophysiology of recombinant human insulin-induced lipoatrophy. RESEARCH DESIGN AND METHODS We performed immunologic laboratory evaluation and skin testing for different insulin analogs and diluents in patients with type 1 diabetes and severe insulin-induced local lipoatrophy. Subcutaneous adipose tissue biopsies of areas of acute (7 days) and chronic insulin a...
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Localized acanthosis nigricans at the insulin injection site is a rare skin disorder in patients with diabetes mellitus. We report co-existence of acanthosis nigricans and lipoatrophy at injection sites in the same patient with type 1 DM. A 23 year old male patient with a history type 1 DM for 11 years was admitted to hospital due to recurrent diabetic ketoacidosis attacks. There were two lesio...
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A 46-year-old Japanese woman with type 2 diabetes noticed a depression in her right anterior abdomen where she had previously injected insulin for approximately 9months (humanneutral protamine Hagedorn insulin and insulin lispro), and this lesion expanded to her right groin. About 18 months after the insulin injections were stopped, a second depression lesion appearedonher left buttockwhere she...
متن کاملHuman insulin-induced lipoatrophy: a successful treatment with glucocorticoid.
B efore the development of purified insulin in the 1970s, lipoatrophy was a common complication of insulin therapy (1,2). With the arrival of human insulin, lipoatrophy has decreased dramatically, becoming a rare problem in clinical practice. Lipoatrophies are considered an adverse immunological side effect of insulin therapy, and in some cases they are mediated by a local high production of tu...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1982
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.57.8.638-b